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TrkB 抑制剂

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产品目录号: A13877


产品名 目录号 价格 数量
ANA-12 10mg A13877-10
¥ 1,100.00
ANA-12 25mg A13877-25
¥ 2,100.00
ANA-12 50mg A13877-50
¥ 3,600.00



ANA-12 is a TrkB receptor antagonist that demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively.





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Chemical Information

目录号 A13877
Mechanism of action Inhibitor
分子量 407.49
化学分子式 C22H21N3O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 219766-25-3
Synonyms ANA12, ANA 12
化学名称 N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carb


ANA-12 is a TrkB receptor antagonist that demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively.
10 nM(Kd)


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.54 mL 122.7 mL 245.4mL
0.5 mM 4.91 mL 24.54 mL 49.08 mL
1 mM 2.45 mL 12.27 mL 24.54 mL
5 mM 0.49 mL 2.45 mL 4.91 mL

*The above data is based on the productmolecular weight 407.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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