ANA-12
目录号: A13877
TrkB 抑制剂
ANA-12 是一种 TrkB 受体拮抗剂,其具有 双位点作用模式,通过非竞争性方式阻止 BDNF 的激活。
| Discription | ANA-12 is a TrkB receptor antagonist that demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively. | ||
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| 目录号 | A13877 |
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| 分子式 | C22H21N3O3S |
| 分子量 | 407.49 |
| CAS号 | 219766-25-3 |
| SMILES | O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O |
| 其他名称 | ANA12, ANA 12 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 33 mg/mL (80.97 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 1 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.54 mL | 122.7 mL | 245.4 mL |
| 0.5 mM | 4.91 mL | 24.54 mL | 49.08 mL |
| 1 mM | 2.45 mL | 12.27 mL | 24.54 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.91 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2