Anti-CD163 (OR2805) is a human monoclonal antibody of the IgG1 subclass designed to specifically target CD163, also known as scavenger receptor cysteine-rich type 1 protein M130. This antibody exhibits potential immunomodulating and antineoplastic properties by selectively binding to CD163, which is prominently expressed on immunosuppressive tumor-associated macrophages (TAMs) within the tumor microenvironment (TME). By binding to CD163, Anti-CD163 (OR2805) effectively inhibits the interaction of CD163 with its natural ligands, thereby modulating the immunosuppressive activity of TAMs and potentially enhancing antitumor immune responses. This mechanism positions Anti-CD163 (OR2805) as a valuable tool for research in cancer immunology and therapeutic development.
Anti-CD163 (OR2805) is a human monoclonal antibody of the IgG1 subclass designed to specifically target CD163, also known as scavenger receptor cysteine-rich type 1 protein M130. This antibody exhibits potential immunomodulating and antineoplastic properties by selectively binding to CD163, which is prominently expressed on immunosuppressive tumor-associated macrophages (TAMs) within the tumor microenvironment (TME). By binding to CD163, Anti-CD163 (OR2805) effectively inhibits the interaction of CD163 with its natural ligands, thereby modulating the immunosuppressive activity of TAMs and potentially enhancing antitumor immune responses. This mechanism positions Anti-CD163 (OR2805) as a valuable tool for research in cancer immunology and therapeutic development.
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