TAK-701 is a humanized monoclonal antibody that targets human hepatocyte growth factor (HGF), exhibiting potential antineoplastic properties. This antibody is specifically designed to bind to HGF, a multifunctional cytokine involved in cell growth, motility, and morphogenesis of various tissues, with a particular focus on its role in tumorogenesis. TAK-701 has shown efficacy in reversing gefitinib resistance in non-small-cell lung cancer (NSCLC), suggesting its utility in enhancing response rates to conventional therapies in resistant cancer cells. This makes it a valuable tool for research in cancer treatment modalities, particularly in understanding and overcoming drug resistance mechanisms in NSCLC.
TAK-701 is a humanized monoclonal antibody that targets human hepatocyte growth factor (HGF), exhibiting potential antineoplastic properties. This antibody is specifically designed to bind to HGF, a multifunctional cytokine involved in cell growth, motility, and morphogenesis of various tissues, with a particular focus on its role in tumorogenesis. TAK-701 has shown efficacy in reversing gefitinib resistance in non-small-cell lung cancer (NSCLC), suggesting its utility in enhancing response rates to conventional therapies in resistant cancer cells. This makes it a valuable tool for research in cancer treatment modalities, particularly in understanding and overcoming drug resistance mechanisms in NSCLC.
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