Antihistamine-1
目录号: A20515
Antihistamine-1 是一种 H1-抗组胺药(Ki=6.9 nM),具有可接受的血脑屏障穿透能力,同时也是 CYP2D6 和 hERG 通道的抑制剂,其 IC50 分别为 5.4 和 0.8 微米。
Discription | Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively. | |||||
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Cell Research |
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目录号 | A20515 |
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分子式 | C23H24FN5 |
分子量 | 389.47 |
CAS号 | 1186430-60-3 |
SMILES | CC1=CN(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)N=C1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2