Apatinib

Name: Apatinib
SKU: A17249
Price: 833 CNY
Rating: 5 (288 reviews)

目录号: A17249

VEGFR-2 抑制剂

Apatinib（YN968D1）是一种口服生物利用度的酪氨酸激酶抑制剂，它选择性地针对VEGFR-2，IC50为1 nM。

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Grouped product items
规格	价格	库存
5mg	¥833.00	现货
10mg	¥1,435.00	现货
50mg	¥4,249.00	现货
100mg	¥8,498.00	现货
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Data Sheet

SDS

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生物活性

Discription	Apatinib (YN968D1) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 with an IC50 of 1 nM.

产品信息

目录号	A17249
分子式	C25H27N5O4S
分子量	493.58
CAS号	1218779-75-9
SMILES	O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC=C(C4(C#N)CCCC4)C=C3.CS(=O)(O)=O
其他名称	YN968D1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	20 mg/mL (40.52 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.26 mL	101.3 mL	202.6 mL
0.5 mM	4.05 mL	20.26 mL	40.52 mL
1 mM	2.03 mL	10.13 mL	20.26 mL
5 mM	0.41 mL	2.03 mL	4.05 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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