APD597 (JNJ-38431055)
目录号: A15452
GPR119 激动剂
APD597 是一种针对 GPR119 受体的激动剂,旨在治疗2型糖尿病,其对 hGPR119 的 EC50 为46 nM。
Discription | APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119. |
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目录号 | A15452 |
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分子式 | C21H29N5O6S |
分子量 | 479.55 |
CAS号 | 897732-93-3 |
SMILES | CC1=C(C=CC(=N1)S(=O)(=O)C)NC2=C(C(=NC=N2)OC3CCN(CC3)C(=O)OC(C)C)OC |
其他名称 | JNJ-38431055, APD-597, APD 597, JNJ38431055, JNJ 38431055 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 89 mg/mL (185.58 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.85 mL | 104.26 mL | 208.53 mL |
0.5 mM | 4.17 mL | 20.85 mL | 41.71 mL |
1 mM | 2.09 mL | 10.43 mL | 20.85 mL |
5 mM | 0.42 mL | 2.09 mL | 4.17 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2