APG-115

目录号: A12575

MDM2 inhibitor

APG-115

APG-115 Chemical Structure

CAS NO. 1818393-16-6

APG-115 (AA-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively.

库存: 现货

规格 价格 数量
1 mg
¥ 3,200.00
5 mg
¥ 9,600.00
10 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

APG-115 (AA-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.56 mL 77.81 mL 155.62 mL
0.5 mM 3.11 mL 15.56 mL 31.12 mL
1 mM 1.56 mL 7.78 mL 15.56 mL
5 mM 0.31 mL 1.56 mL 3.11 mL

*The above data is based on the productmolecular weight 642.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12575
作用机制 Inhibitor (抑制剂)
M. Wt 642.59
Formula C34H38Cl2FN3O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1818393-16-6
Synonyms APG115, APG 115
SMILES O=C1NC2=CC(Cl)=CC=C2[C@]13C4(CCCCC4)N(CC)[C@@H](C(NC56CCC(CC6)(C(O)=O)CC5)=O)[C@@H]3C7=C(C(Cl)=CC=C7)F

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