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API-1

目录号: A22093
Akt 抑制剂
API-1(NSC 177223)是一种强效的Akt抑制剂,它通过GSK3依赖的、β-TrCP和FBXW7介导的Mcl-1降解,从而诱导凋亡。
Grouped product items
规格 价格 库存 数量
1mg
¥490.00
现货
5mg
¥1,050.00
现货
10mg
¥1,785.00
现货
25mg
¥2,975.00
现货
50mg
¥4,095.00
现货
100mg
¥5,740.00
现货
200mg
¥7,595.00
现货
10mM * 1mL in DMSO
¥1,190.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis.
产品信息
目录号 A22093
分子式 C13H15N5O6
分子量 337.29
CAS号 36707-00-3
SMILES O=C(C1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=NC=NC(N)=C3C1=O)N
其他名称 API1; API 1; NSC177233.
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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