Apilimod
目录号: A13794
IL-12/IL-23 抑制剂
Apilimod 是一种强效的 IL-12/IL-23 抑制剂,在 IFN-r/LPS 刺激的人类 PBMCs 培养中,STA-5326 强烈抑制 IL-12 的产生,其 IC50 为 10 nM。
Discription | Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM. | |||||
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Cell Research |
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目录号 | A13794 |
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分子式 | C23H26N6O2 |
分子量 | 418.498 |
CAS号 | 541550-19-0 |
SMILES | CC1=CC=CC(=C1)/C=N/NC2=NC(=NC(=C2)N3CCOCC3)OCCC4=CC=CC=N4 |
其他名称 | Sta 5326, Sta5326, Sta-5326 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 74 mg/mL (176.82 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.89 mL | 119.47 mL | 238.95 mL |
0.5 mM | 4.78 mL | 23.89 mL | 47.79 mL |
1 mM | 2.39 mL | 11.95 mL | 23.89 mL |
5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2