Apilimod

目录号: A13794

IL-12/IL-23 inhibitor

Apilimod

Apilimod Chemical Structure

CAS NO. 541550-19-0

Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 770.00
25 mg
¥ 1,350.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM.
In vitro DMSO 74 mg/mL (176.82 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.89 mL 119.47 mL 238.95 mL
0.5 mM 4.78 mL 23.89 mL 47.79 mL
1 mM 2.39 mL 11.95 mL 23.89 mL
5 mM 0.48 mL 2.39 mL 4.78 mL

*The above data is based on the productmolecular weight 418.498. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13794
作用机制 Inhibitor (抑制剂)
M. Wt 418.498
Formula C23H26N6O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 541550-19-0
Synonyms Sta 5326, Sta5326, Sta-5326
SMILES CC1=CC=CC(=C1)/C=N/NC2=NC(=NC(=C2)N3CCOCC3)OCCC4=CC=CC=N4

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