(+)-Apogossypol

目录号: A16316

Bcl-2 family inhibitor

(+)-Apogossypol Chemical Structure

CAS NO. 66389-74-0

(+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins; competing with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.

库存: 现货

规格 价格 数量
5 mg
¥ 3,200.00
10 mg
¥ 5,800.00
50 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

(+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins; competing with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.1 mL 216.2 mL
0.5 mM 4.32 mL 21.62 mL 43.24 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16316
MECHANISM OF ACTION Inhibitor
M. Wt 462.53
Formula C28H30O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 66389-74-0
Synonyms Apogossypol, NSC736630
SMILES CC(C=C1C(C(C)C)=C(O)C(O)=CC1=C2O)=[C@]2[C@@]3=C(C)C=C4C(C=C(O)C(O)=C4C(C)C)=C3O

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