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Apoptosis Activator 2

Apoptosis Activator

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产品目录号: A11944

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Apoptosis Activator 2 10mg A11944-10
¥ 500.00
Apoptosis Activator 2 25mg A11944-25
¥ 1,100.00
Apoptosis Activator 2 50mg A11944-50
¥ 1,800.00
Apoptosis Activator 2 100mg A11944-100
¥ 2,850.00
Apoptosis Activator 2 10mM * 1mL in DMSO A11944-10mM-D
¥ 550.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells

Apoptosis Activator 2

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Chemical Information

目录号 A11944
Mechanism of action Activator
分子量 306.1
化学分子式 C15H9Cl2NO2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 79183-19-0
Synonyms N/A
SMILES code C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl
化学名称 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione

生物活性

Description
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells
Targets
Caspase-3

溶解性

Solubility (25°C)* In vitro DMSO 61 mg/mL (199.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.67 mL 163.35 mL 326.69mL
0.5 mM 6.53 mL 32.67 mL 65.34 mL
1 mM 3.27 mL 16.33 mL 32.67 mL
5 mM 0.65 mL 3.27 mL 6.53 mL

*The above data is based on the productmolecular weight 306.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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