Apoptozole

Name: Apoptozole
SKU: A21177

目录号: A21177

Hsc70 and Hsp70 inhibitor

Apoptozole Chemical Structure

CAS NO. 1054543-47-3

Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14?μM, respectively, and can induce apoptosis.

库存：现货

规格	价格	数量
5 mg	￥ 500.00
10 mg	￥ 850.00
50 mg	￥ 2,530.00
100 mg	￥ 5,060.00

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生物活性

Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14?μM, respectively, and can induce apoptosis.

溶解度 *

In vitro (25°C)	DMSO	96 mg/mL (153.46 mM)
	Water	Insoluble
	Ethanol	24 mg/mL (38.36 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.99 mL	79.93 mL	159.86 mL
0.5 mM	3.2 mL	15.99 mL	31.97 mL
1 mM	1.6 mL	7.99 mL	15.99 mL
5 mM	0.32 mL	1.6 mL	3.2 mL

*The above data is based on the productmolecular weight 625.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21177
作用机制	Inhibitor (抑制剂)
M. Wt	625.56
Formula	C33H25F6N3O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1054543-47-3
Synonyms	Apoptosis Activator VII
SMILES	NC(C(C=C1)=CC=C1CN2C(C3=CC=C(OC)C=C3)=C(C4=CC=C(OC)C=C4)N=C2C5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=O