Apremilast (CC 10004)

目录号: A11289

PDE4 Inhibitor

Apremilast (CC 10004)

Apremilast (CC 10004) Chemical Structure

CAS NO. 608141-41-9

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.

库存: 现货

规格 价格 数量
2 mg
¥ 400.00
5 mg
¥ 600.00
10 mg
¥ 900.00
25 mg
¥ 1,200.00
200 mg
¥ 4,500.00
10mM * 1mL in DMSO
¥ 650.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.
In vitro (25°C) DMSO 92 mg/mL (199.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.72 mL 108.58 mL 217.16 mL
0.5 mM 4.34 mL 21.72 mL 43.43 mL
1 mM 2.17 mL 10.86 mL 21.72 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11289
MECHANISM OF ACTION Inhibitor
M. Wt 460.5
Formula C22H24N2O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 608141-41-9
Synonyms CC10004, CC-10004
SMILES CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC

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