APS-2-79 HCl

Name: APS-2-79 HCl
SKU: A16175

目录号: A16175

KSR/Ras 抑制剂

APS-2-79 HCl Chemical Structure

CAS NO. 2002381-31-7

APS-2-79 HCl，稳定KSR（Ras激酶抑制剂）失活状态并拮抗致癌性Ras信号（IC50值为120 nM，对抗KSR2的ATP-生物素探针标记）的小分子。

库存：现货

规格	价格	数量
5 mg	￥ 450.00
10 mg	￥ 650.00
50 mg	￥ 2,100.00

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生物活性

APS-2-79 HCl，稳定KSR（Ras激酶抑制剂）失活状态并拮抗致癌性Ras信号（IC50值为120 nM，对抗KSR2的ATP-生物素探针标记）的小分子。

靶点信息

KSR2
120 nM

溶解度 *

In vitro	DMSO	82 mg/mL (193.44 mM)
	Water	Insoluble
	Ethanol	27 mg/mL (63.69 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.59 mL	117.96 mL	235.91 mL
0.5 mM	4.72 mL	23.59 mL	47.18 mL
1 mM	2.36 mL	11.8 mL	23.59 mL
5 mM	0.47 mL	2.36 mL	4.72 mL

*The above data is based on the productmolecular weight 423.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16175
作用机制	Inhibitor (抑制剂)
M. Wt	423.89
Formula	C23H21N3O3.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2002381-31-7
Synonyms	KSR/Ras Inhibitor
SMILES	CC1=C(C=CC(=C1)OC2=CC=CC=C2)NC3=NC=NC4=CC(=C(C=C43)OC)OC.Cl