APS-2-79 HCl

Name: APS-2-79 HCl
SKU: A16175
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A16175

KSR/Ras 抑制剂

APS-2-79 HCl 是一种小分子，能够稳定 KSR（Ras 的激酶抑制剂）的非活性状态，并抗拒致癌 Ras 信号传导（对 KSR2 的 ATP-生物素探针标记的 IC50 值为 120 nM）。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥420.00	现货
10mg	¥700.00	现货
25mg	¥1,680.00	现货
50mg	¥2,870.00	现货
100mg	¥4,095.00	现货
500mg	¥8,995.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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Data Sheet

SDS

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生物活性

Discription

APS-2-79 HCl, small molecule that stabilizes the KSR (Kinase suppressor of Ras) inactive state and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2).

Targets

Target	Value

产品信息

目录号	A16175
分子式	C23H21N3O3.HCl
分子量	423.89
CAS号	2002381-31-7
SMILES	CC1=C(C=CC(=C1)OC2=CC=CC=C2)NC3=NC=NC4=CC(=C(C=C43)OC)OC.Cl
其他名称	KSR/Ras Inhibitor
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	82 mg/mL (193.44 mM)
	Water	Insoluble
	Ethanol	27 mg/mL (63.69 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.59 mL	117.96 mL	235.91 mL
0.5 mM	4.72 mL	23.59 mL	47.18 mL
1 mM	2.36 mL	11.8 mL	23.59 mL
5 mM	0.47 mL	2.36 mL	4.72 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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