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IRE1?? 抑制剂

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产品目录号: A13828


产品名 目录号 价格 数量
APY29 10mg A13828-10
¥ 1,200.00
APY29 25mg A13828-25
¥ 2,500.00
APY29 50mg A13828-50
¥ 4,000.00



APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.





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Chemical Information

目录号 A13828
Mechanism of action Inhibitor
分子量 332.36
化学分子式 C17H16N8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1216665-49-4
Synonyms APY 29, Apy-29
SMILES code C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
化学名称 N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine


APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.09 mL 150.44 mL 300.88mL
0.5 mM 6.02 mL 30.09 mL 60.18 mL
1 mM 3.01 mL 15.04 mL 30.09 mL
5 mM 0.6 mL 3.01 mL 6.02 mL

*The above data is based on the productmolecular weight 332.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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