APY29
目录号: A13828
IRE1α 抑制剂
APY29 抑制 IRE1α 自磷酸化(IC50 = 280 nM)并激活 IRE1α RNase 活性。
| Discription | APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity. |
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| 目录号 | A13828 |
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| 分子式 | C17H16N8 |
| 分子量 | 332.36 |
| CAS号 | 1216665-49-4 |
| SMILES | C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5 |
| 其他名称 | APY 29, Apy-29 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 27 mg/mL (81.24 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.09 mL | 150.44 mL | 300.88 mL |
| 0.5 mM | 6.02 mL | 30.09 mL | 60.18 mL |
| 1 mM | 3.01 mL | 15.04 mL | 30.09 mL |
| 5 mM | 0.6 mL | 3.01 mL | 6.02 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2