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APY29

促销

IRE1?? 抑制剂

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产品目录号: A13828

库存状态:中国现货中国现货

产品名 目录号 价格 数量
APY29 10mg A13828-10
¥ 1,200.00
APY29 25mg A13828-25
¥ 2,500.00
APY29 50mg A13828-50
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.

APY29

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Chemical Information

目录号 A13828
Mechanism of action Inhibitor
分子量 332.36
化学分子式 C17H16N8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1216665-49-4
Synonyms APY 29, Apy-29
SMILES code C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
化学名称 N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine

生物活性

Description
APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.09 mL 150.44 mL 300.88mL
0.5 mM 6.02 mL 30.09 mL 60.18 mL
1 mM 3.01 mL 15.04 mL 30.09 mL
5 mM 0.6 mL 3.01 mL 6.02 mL

*The above data is based on the productmolecular weight 332.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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