AR-C155858

目录号: A11293

MCT1 and MCT2 抑制剂

AR-C155858 Chemical Structure

CAS NO. 496791-37-8

AR-C155858是单羧酸转运蛋白mct1和mct2的有效抑制剂,它们与涉及跨膜螺旋7-10的细胞内位点结合。

库存: 现货

规格 价格 数量
5 mg
¥ 3,600.00
10 mg
¥ 6,000.00
25 mg
¥ 12,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AR-C155858是单羧酸转运蛋白mct1和mct2的有效抑制剂,它们与涉及跨膜螺旋7-10的细胞内位点结合。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.34 mL 216.68 mL
0.5 mM 4.33 mL 21.67 mL 43.34 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11293
MECHANISM OF ACTION Inhibitor
M. Wt 461.5
Formula C21H27N5O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 496791-37-8
Synonyms AR-C 155858
SMILES CC1=C(C(=NN1)C)CC2=C(C3=C(S2)N(C(=O)N(C3=O)C)CC(C)C)C(=O)N4C[C@@H](CO4)O
1. Ovens et al (2010) The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein. Biochem.J. 431 217. PMID: 20695846.
2.Ovens et al (2010) AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. Biochem.J. 425 523. PMID: 19929853.

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