ARQ-092 (Miransertib)
目录号: A16286
AKT 抑制剂
ARQ 092 是一种口服活性、高效和选择性的 AKT 抑制剂,其 IC50 值分别为:5.0 nM(AKT1);4.5 nM(AKT2);16 nM(AKT3)。
Discription | ARQ 092 is an oral activie, potent and selective AKT inhibitor with IC50 values: 5.0 nM (AKT1); 4.5 nM (AKT2); 16 nM (AKT3). | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A16286 |
---|---|
分子式 | C27H24N6 |
分子量 | 432.53 |
CAS号 | 1313881-70-7 |
SMILES | NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5 |
其他名称 | ARQ092, ARQ 092 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 8 mg/mL (18.49 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.12 mL | 115.6 mL | 231.2 mL |
0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2