ARRY-380 (Irbinitinib)

Name: ARRY-380 (Irbinitinib)
SKU: A16413
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A16413

HER2 抑制剂

ARRY-380 是一种口服生物利用度的人表皮生长因子受体酪氨酸激酶ErbB-2（也称为HER2）抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥840.00	现货
50mg	¥1,330.00	现货
100mg	¥2,520.00	现货
500mg	¥6,020.00	现货
1g	¥8,295.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

ARRY-380 is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A16413
分子式	C26H24N8O2
分子量	480.52
CAS号	937263-43-9
SMILES	CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
其他名称	Tucatinib, ONT-380, Irbinitinib
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	87 mg/mL (181.05 mM)
	Water	Insoluble
	Ethanol	14 mg/mL (29.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.81 mL	104.05 mL	208.11 mL
0.5 mM	4.16 mL	20.81 mL	41.62 mL
1 mM	2.08 mL	10.41 mL	20.81 mL
5 mM	0.42 mL	2.08 mL	4.16 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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