Artesunate

目录号: A10087

cytochrome oxidase inhibitor

Artesunate

Artesunate Chemical Structure

CAS NO. 88495-63-0

Artesunate is a semisynthetic derivative of artemisinin used to treat malaria. It has also been shown to effective against other parasites such as liver flukes. Artesunate also demonstrates cytotoxic action against cancer cell lines of different tumor types. Artesunate has been shown to inhibit TNF--induced production of proinflammatory cytokines via inhibition of NF-B and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
50 mg
¥ 1,600.00
100 mg
¥ 2,800.00
10mM * 1mL in DMSO
¥ 740.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Artesunate is a semisynthetic derivative of artemisinin used to treat malaria. It has also been shown to effective against other parasites such as liver flukes. Artesunate also demonstrates cytotoxic action against cancer cell lines of different tumor types. Artesunate has been shown to inhibit TNF--induced production of proinflammatory cytokines via inhibition of NF-B and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.
Targets
EXP1(a membrane glutathione S-transferase)
In vitro DMSO 77 mg/mL (200.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol 77 mg/mL (200.3 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.01 mL 130.07 mL 260.15 mL
0.5 mM 5.2 mL 26.01 mL 52.03 mL
1 mM 2.6 mL 13.01 mL 26.01 mL
5 mM 0.52 mL 2.6 mL 5.2 mL

*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10087
MECHANISM OF ACTION Inhibitor
M. Wt 384.4
Formula C19H28O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 88495-63-0
Synonyms N/A
SMILES C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C

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