ARV-771

Name: ARV-771
SKU: A13255
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A13255

BET degrader

ARV-771 是一种基于 PROTAC 技术的强效 BET 降解剂，其对 BRD2(1)、BRD2(2)、BRD3(1)、BRD3(2)、BRD4(1) 和 BRD4(2) 的 Kd 值分别为 34、4.7、8.3、7.6、9.6 和 7.6 nM。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
5mg	¥805.00	现货
10mg	¥1,330.00	现货
25mg	¥2,695.00	现货
50mg	¥4,060.00	现货
100mg	¥5,810.00	现货
*10mM 1mL in DMSO**	¥1,435.00	现货
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Data Sheet

SDS

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生物活性

Discription

ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13255
分子式	C49H60ClN9O7S2
分子量	986.64
CAS号	1949837-12-0
SMILES	CC(C(C(C1=CC=C(Cl)C=C1)=N[C@@H](CC(NCCOCCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C2)[C@@H]2C(N[C@H](C3=CC=C(C(SC=N4)=C4C)C=C3)C)=O)=O)=O)=O)C5=NN=C(C)N65)=C6S7)=C7C
其他名称	ARV771, ARV 771
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	97 mg/mL (98.31 mM)
	Water	Insoluble
	Ethanol	97 mg/mL (98.31 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.14 mL	50.68 mL	101.35 mL
0.5 mM	2.03 mL	10.14 mL	20.27 mL
1 mM	1.01 mL	5.07 mL	10.14 mL
5 mM	0.2 mL	1.01 mL	2.03 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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