AS-252424

Name: AS-252424
SKU: A11099
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A11099

PI3K 抑制剂

AS-252424 是一种针对 PI3K 的强效抑制剂，对 γ 亚型具有选择性。它抑制人类重组的 PI3Kγ、α、β 和 δ，其 IC50 值分别为 30、940、20,000 和 20,000 nM。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥385.00	现货
10mg	¥665.00	现货
25mg	¥1,540.00	现货
50mg	¥2,345.00	现货
100mg	¥3,430.00	现货
500mg	¥7,525.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

AS-252424 is a potent inhibitor of PI3K with selectivity for the γ isoform. It inhibits human recombinant PI3Kγ, α, β, and δ with IC50 values of 30, 940, 20,000, and 20,000 nM respectively.

Targets

Target	Value

产品信息

目录号	A11099
分子式	C14H8FNO4S
分子量	305.3
CAS号	900515-16-4
SMILES	C1=CC(=C(C=C1F)O)C2=CC=C(O2)/C=C\3/C(=O)NC(=O)S3
其他名称	AS252424
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	57 mg/mL (186.71 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+50% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.75 mL	163.77 mL	327.55 mL
0.5 mM	6.55 mL	32.75 mL	65.51 mL
1 mM	3.28 mL	16.38 mL	32.75 mL
5 mM	0.66 mL	3.28 mL	6.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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