AS-605240

Name: AS-605240
SKU: A10088
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10088

PI3K 抑制剂

AS-605240 是一种口服活性的 PI3-kinase γ 抑制剂，它以 ATP 竞争方式抑制人类重组 PI3Kγ、PI3Kα、PI3Kβ 和 PI3Kδ，其 IC50 值分别为 8、60、270 和 300 nM。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥525.00	现货
50mg	¥980.00	现货
100mg	¥1,680.00	现货
200mg	¥2,520.00	现货
500mg	¥4,130.00	现货
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Data Sheet

SDS

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生物活性

Discription

AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10088
分子式	C12H7N3O2S
分子量	257.3
CAS号	648450-29-7
SMILES	C1=CC2=NC=CN=C2C=C1/C=C\3/C(=O)NC(=O)S3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	0.38 mg/mL (1.47 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.87 mL	194.33 mL	388.65 mL
0.5 mM	7.77 mL	38.87 mL	77.73 mL
1 mM	3.89 mL	19.43 mL	38.87 mL
5 mM	0.78 mL	3.89 mL	7.77 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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