AS1842856

Name: AS1842856
SKU: A15871

目录号: A15871

Foxo1 抑制剂

Product Citations (2)

AS1842856 Chemical Structure

CAS NO. 836620-48-5

AS1842856是细胞渗透性抑制剂，可阻断Foxo1的转录活性，IC50为33 nM。它可以直接与活性Foxo1结合，但不能与Ser256磷酸化形式结合。

库存：现货

规格	价格	数量
10 mg	￥ 800.00
25 mg	￥ 1,300.00
50 mg	￥ 1,750.00

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生物活性

AS1842856是细胞渗透性抑制剂，可阻断Foxo1的转录活性，IC50为33 nM。它可以直接与活性Foxo1结合，但不能与Ser256磷酸化形式结合。

靶点信息

Foxo1
33nM

溶解度 *

In vitro	DMSO	23 mg/mL (66.2 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.79 mL	143.93 mL	287.87 mL
0.5 mM	5.76 mL	28.79 mL	57.57 mL
1 mM	2.88 mL	14.39 mL	28.79 mL
5 mM	0.58 mL	2.88 mL	5.76 mL

*The above data is based on the productmolecular weight 347.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15871
作用机制	Inhibitor (抑制剂)
M. Wt	347.38
Formula	C18H22FN3O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	836620-48-5
Synonyms	AS 1842856, AS-1842856
SMILES	O=C1C(C(O)=O)=CN(CC)C2=C1C(N)=C(F)C(NC3CCCCC3)=C2