AS1842856

Name: AS1842856
SKU: A15871
Price: 280 CNY
Rating: 5 (4 reviews)

目录号: A15871

Foxo1 抑制剂

4 篇发表文献

AS1842856 是一种能够穿透细胞的抑制剂，它通过直接结合到活性的 Foxo1 上来阻断 Foxo1 的转录活性，其 IC50 为 33 nM。它不能与 Ser256 磷酸化形式的 Foxo1 结合。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥700.00	现货
50mg	¥1,050.00	现货
100mg	¥1,610.00	现货
200mg	¥2,415.00	现货
500mg	¥4,130.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AS1842856发表的4篇文献

Jungang Lan, .et al. , PLoS Pathog, 2023, Aug 18;19(8) PMID: 37594999

Jiunn-Chang Lin, .et al. , Am J Cancer Res, 2023, Sep 15;13(9):4125-4144 PMID: 37818050

Yuta Tanizaki, .et al. , Commun Biol, 2022, 5: 112 PMID: 35132135

Zhongsheng Zhu, .et al. , BMC Complement Altern Med, 2019, 19: 111 PMID: 31146723

生物活性

Discription

AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.

Targets

Target	Value

产品信息

目录号	A15871
分子式	C18H22FN3O3
分子量	347.38
CAS号	836620-48-5
SMILES	O=C1C(C(O)=O)=CN(CC)C2=C1C(N)=C(F)C(NC3CCCCC3)=C2
其他名称	AS 1842856, AS-1842856
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	23 mg/mL (66.2 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.79 mL	143.93 mL	287.87 mL
0.5 mM	5.76 mL	28.79 mL	57.57 mL
1 mM	2.88 mL	14.39 mL	28.79 mL
5 mM	0.58 mL	2.88 mL	5.76 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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