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AS1842856

Foxo1 抑制剂

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产品目录号: A15871

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AS1842856 10mg A15871-10
¥ 1,100.00
AS1842856 25mg A15871-25
¥ 2,500.00
AS1842856 50mg A15871-50
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.

AS1842856

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Chemical Information

目录号 A15871
Mechanism of action Inhibitor
分子量 347.38
化学分子式 C18H22FN3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 836620-48-5
Synonyms AS 1842856, AS-1842856
SMILES code N/A
化学名称 3-?Quinolinecarboxylic acid, 5-?amino-?7-?(cyclohexylamino)?-?1-?ethyl-?6-?fluoro-?1,?4-?dihydro-?4-?oxo-

生物活性

Description
AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.
Targets
Foxo1
33nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.79 mL 143.93 mL 287.87mL
0.5 mM 5.76 mL 28.79 mL 57.57 mL
1 mM 2.88 mL 14.39 mL 28.79 mL
5 mM 0.58 mL 2.88 mL 5.76 mL

*The above data is based on the productmolecular weight 347.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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