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AS703026 (Pimasertib)

目录号: A10089
MEK1/2 抑制剂
AS703026 是一种新型、选择性、口服生物利用度的 MEK1/2 抑制剂,它能抑制 MM 细胞的生长和存活,以及细胞因子诱导的破骨细胞分化。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥245.00
现货
10mg
¥350.00
现货
25mg
¥595.00
现货
50mg
¥1,015.00
现货
100mg
¥1,575.00
现货
200mg
¥2,065.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation.
Targets
Target Value
产品信息
目录号 A10089
分子式 C15H15FIN3O3
分子量 431.2
CAS号 1236699-92-5
SMILES C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O
其他名称 MSC1936369B
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO 78 mg/mL (180.89 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC+0.25% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.19 mL 115.96 mL 231.91 mL
0.5 mM 4.64 mL 23.19 mL 46.38 mL
1 mM 2.32 mL 11.6 mL 23.19 mL
5 mM 0.46 mL 2.32 mL 4.64 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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