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Asciminib

Asciminib

Name: Asciminib
SKU: A19658

目录号: A19658

Bcr-Abl inhibitor

Asciminib Chemical Structure

CAS NO. 1492952-76-7

Asciminib (ABL001) is a potent and selective allosteric Bcr-Abl inhibitor; inhibits Ba/F3 cells grown with an IC50 of 0.25 nM.

库存：现货

规格	价格	数量
1 mg	￥ 630.00
5 mg	￥ 1,890.00
10 mg	￥ 3,220.00
50 mg	￥ 9,660.00

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生物活性

Asciminib (ABL001) is a potent and selective allosteric Bcr-Abl inhibitor; inhibits Ba/F3 cells grown with an IC50 of 0.25 nM.

溶解度 *

In vitro	DMSO	76 mg/mL (168.94 mM)
	Ethanol	76 mg/mL (168.94 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.23 mL	111.15 mL	222.3 mL
0.5 mM	4.45 mL	22.23 mL	44.46 mL
1 mM	2.22 mL	11.12 mL	22.23 mL
5 mM	0.44 mL	2.22 mL	4.45 mL

*The above data is based on the productmolecular weight 449.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19658
M. Wt	449.84
Formula	C20H18ClF2N5O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1492952-76-7
Synonyms	ABL001, ABL 001, ABL-001
SMILES	O=C(C1=CC(C2=NNC=C2)=C(N3C[C@H](O)CC3)N=C1)NC4=CC=C(OC(F)(Cl)F)C=C4