ASP5878

Name: ASP5878
SKU: A20611
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A20611

FGFR 1/2/3/4 抑制剂

ASP5878 是一种口服活性抑制剂，针对 FGFR 1, 2, 3, 和 4，其 IC50 值分别为 0.47 nM, 0.6 nM, 0.74 nM 和 3.5 nM，用于抑制 FGFR 1, 2, 3, 和 4 的激酶活性。ASP5878 具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
5mg	¥1,085.00	现货
10mg	¥1,680.00	现货
25mg	¥3,080.00	现货
50mg	¥4,340.00	现货
100mg	¥6,090.00	现货
*10mM 1mL in DMSO**	¥1,190.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

ASP5878 is an oral active inhibitor of FGFR 1, 2, 3, and 4, with IC50 values of 0.47 nM, 0.6 nM, 0.74 nM and 3.5 nM for FGFR 1, 2, 3, and 4 kinase activity. ASP5878 has potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20611
分子式	C18H19F2N5O4
分子量	407.37
CAS号	1453208-66-6
SMILES	OCCN1N=CC(NC2=NC=C(OCC3=C(F)C(OC)=CC(OC)=C3F)C=N2)=C1
其他名称	ASP 5878, ASP-5878
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	75 mg/mL (184.1 mM)
	Water	Insoluble
	Ethanol	4 mg/mL (9.81 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.55 mL	122.74 mL	245.48 mL
0.5 mM	4.91 mL	24.55 mL	49.1 mL
1 mM	2.45 mL	12.27 mL	24.55 mL
5 mM	0.49 mL	2.45 mL	4.91 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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