ASP8273 (Naquotinib)

Name: ASP8273 (Naquotinib)
SKU: A14408
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A14408

irreversible EGFR 抑制剂

ASP8273 是一种口服可用的、不可逆的、第三代、突变选择性的表皮生长因子受体（EGFR）抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥700.00	现货
10mg	¥1,330.00	现货
25mg	¥3,045.00	现货
50mg	¥4,865.00	现货
100mg	¥7,875.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

ASP8273 is an orally available, irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A14408
分子式	C30H42N8O3
分子量	562.72
CAS号	1448232-80-1
SMILES	O=C(C1=NC(CC)=C(O[C@H]2CN(C(C=C)=O)CC2)N=C1NC3=CC=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)N
其他名称	Naquotinib (free base)
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 50 mg/mL (88.85 mM)
	Water	Insoluble
	Ethanol	Warmed: 96 mg/mL (170.6 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.77 mL	88.85 mL	177.71 mL
0.5 mM	3.55 mL	17.77 mL	35.54 mL
1 mM	1.78 mL	8.89 mL	17.77 mL
5 mM	0.36 mL	1.78 mL	3.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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