AST 487

目录号: A15003

RET kinase 抑制剂

AST 487

AST 487 Chemical Structure

CAS NO. 630124-46-8

AST487是Ret激酶抑制剂/FLT3抑制剂,对Ret的IC50为0.88 uM。

库存: 现货

规格 价格 数量
5 mg
¥ 2,200.00
10 mg
¥ 4,000.00
50 mg
¥ 8,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AST487是Ret激酶抑制剂/FLT3抑制剂,对Ret的IC50为0.88 uM。
In vitro DMSO 89 mg/mL (168.06 mM)
Water Insoluble
Ethanol 29 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.88 mL 94.42 mL 188.84 mL
0.5 mM 3.78 mL 18.88 mL 37.77 mL
1 mM 1.89 mL 9.44 mL 18.88 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15003
作用机制 Inhibitor (抑制剂)
M. Wt 529.56
Formula C26H30F3N7O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 630124-46-8
Synonyms NVP-AST 487
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F

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