AST 487
目录号: A15003
RET kinase 抑制剂
AST487 是一种 Ret 激酶抑制剂/FLT3 抑制剂，其对 Ret 的 IC50 为 0.88 uM。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | AST487 is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret. |
|---|
产品信息
| 目录号 | A15003 |
|---|---|
| 分子式 | C26H30F3N7O2 |
| 分子量 | 529.56 |
| CAS号 | 630124-46-8 |
| SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F |
| 其他名称 | NVP-AST 487 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 89 mg/mL (168.06 mM) | |
| Water | Insoluble | ||
| Ethanol | 29 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.88 mL | 94.42 mL | 188.84 mL |
| 0.5 mM | 3.78 mL | 18.88 mL | 37.77 mL |
| 1 mM | 1.89 mL | 9.44 mL | 18.88 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 AST 487 | AST 487 供应商 | AST 487 花费 | AST 487 生产商 | 订购 AST 487 | AST 487 代理商
| 购买 630124-46-8 | 630124-46-8 供应商 | 630124-46-8 花费 | 630124-46-8 生产商 | 订购 630124-46-8 | 630124-46-8 代理商