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AST 487

RET kinase 抑制剂

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产品目录号: A15003


产品名 目录号 价格 数量
AST 487 5mg A15003-5
¥ 2,200.00
AST 487 10mg A15003-10
¥ 4,000.00
AST 487 50mg A15003-50
¥ 8,200.00



AST487 is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret.

AST 487




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Chemical Information

目录号 A15003
Mechanism of action Inhibitor
分子量 529.56
化学分子式 C26H30F3N7O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 630124-46-8
Synonyms NVP-AST 487
化学名称 1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea


AST487 is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.88 mL 94.42 mL 188.84mL
0.5 mM 3.78 mL 18.88 mL 37.77 mL
1 mM 1.89 mL 9.44 mL 18.88 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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