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ASTX660是X染色体连锁的凋亡蛋白抑制剂（XIAP）和细胞IAP 1（cIAP1）的口服生物利用型非拟肽拮抗剂，具有潜在的抗肿瘤和促凋亡活性。1799328-86-1 (free base) 1799328-50-9 (HCl) 1799328-90-7 (mesylate) 1799328-88-3 (sulfate)
| In vitro | DMSO | 93 mg/mL (172.32 mM) | |
| Water | Insoluble | ||
| Ethanol | 93 mg/mL (172.32 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.53 mL | 92.65 mL | 185.29 mL |
| 0.5 mM | 3.71 mL | 18.53 mL | 37.06 mL |
| 1 mM | 1.85 mL | 9.26 mL | 18.53 mL |
| 5 mM | 0.37 mL | 1.85 mL | 3.71 mL |
*The above data is based on the productmolecular weight 539.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16996 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 539.69 |
| Formula | C30H42FN5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1799328-86-1 |
| Synonyms | ASTX660, ASTX 660 |
| SMILES | OCC1=NC2=C(N(CC2(C)C)C(CN3[C@@H](CN4[C@H](C)COCC4)CN[C@H](C)C3)=O)C=C1CC5=CC=C(F)C=C5 |
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