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Asunaprevir (BMS-650032)

促销

NS3 protease 抑制剂

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产品目录号: A11295

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Asunaprevir 5mg A11295-5
¥ 1,800.00
Asunaprevir 10mg A11295-10
¥ 3,000.00
Asunaprevir 25mg A11295-25
¥ 5,500.00
Asunaprevir 50mg A11295-50
¥ 8,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.

Asunaprevir (BMS-650032)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Asunaprevir (BMS-650032) 发表的文献 (5)
  • Fay EJ, .et al. Engineered Small-Molecule Control of Influenza A Virus Replication, J Virol, 2018, Fay EJ PMID: 30282710
  • Bennie Lemmens, .et al. DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation, Mol Cell, 2018, Jul 5; 71(1): 117每128.e3 PMID: 30008317
  • Ueda Y, .et al. Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems, Virus Res, 2017, May 2;235:37-48 PMID: 28322919
  • Furihata T, .et al. Differential inhibition features of direct-acting anti-hepatitis C virus agents against human organic anion transporting polypeptide 2B1, Int J Antimicrob Agents, 2015, Oct;46(4):381-8 PMID: 26163159
  • Tomomi Furihata, .et al. Different Interaction Profiles of Direct-Acting Anti-Hepatitis C Virus Agents with Human Organic Anion Transporting Polypeptides, Antimicrob Agents Chemother, 2014, 58(8): 4555每4564. PMID: 24867984

Chemical Information

目录号 A11295
Mechanism of action Inhibitor
分子量 748.3
化学分子式 C35H46ClN5O9S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 630420-16-5
Synonyms BMS650032, ASV
SMILES code CC(C)(C)C(C(=O)N1CC(CC1C(=O)NC2(CC2C=C)C(=O)NS(=O)(=O)C3CC3)OC4=NC=C(C5=C4C= C(C=C5)Cl)OC)NC(=O)OC(C)(C)C
化学名称 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropyl}-L-prolinamide

生物活性

Description
Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.36 mL 66.82 mL 133.64mL
0.5 mM 2.67 mL 13.36 mL 26.73 mL
1 mM 1.34 mL 6.68 mL 13.36 mL
5 mM 0.27 mL 1.34 mL 2.67 mL

*The above data is based on the productmolecular weight 748.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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