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AT-101

Bcl-2 抑制剂

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产品目录号: A15004

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AT-101 10mg A15004-10
¥ 800.00
AT-101 50mg A15004-50
¥ 3,300.00
AT-101 100mg A15004-100
¥ 6,600.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32μM, 0.48μM and 0.18μM.

AT-101

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Chemical Information

目录号 A15004
Mechanism of action Inhibitor
分子量 518.55
化学分子式 C30H30O8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 90141-22-3
Synonyms (R)-(-)-Gossypol, R-(-)-gossypol acetic acid, AT 101, AT101
SMILES code CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C
化学名称 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde

生物活性

Description
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32μM, 0.48μM and 0.18μM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.28 mL 96.42 mL 192.85mL
0.5 mM 3.86 mL 19.28 mL 38.57 mL
1 mM 1.93 mL 9.64 mL 19.28 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 518.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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