AT101 acetic acid

Name: AT101 acetic acid
SKU: A13578
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A13578

pan Bcl-2 抑制剂

AT101，即棉酚乙酸的 R-(-) 对映体，与 Bcl-2、Bcl-xL 和 Mcl-1 结合，其 Ki 分别为 0.32 微米、0.48 微米和 0.18 微米；不抑制 BIR3 域和 BID。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥1,190.00	现货
50mg	¥2,030.00	现货
100mg	¥3,360.00	现货
500mg	¥7,385.00	现货
1g	¥9,975.00	现货
*10mM 1mL in DMSO**	¥819.00	现货
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Data Sheet

SDS

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生物活性

Discription

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID

Targets

Target	Value

产品信息

目录号	A13578
分子式	C30H30O8.C2H4O2
分子量	578.61
CAS号	866541-93-7
SMILES	CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O
其他名称	AT-101, AT 101
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	108 mg/mL (186.65 mM)
	Water	Insoluble
	Ethanol	83 mg/mL
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.28 mL	86.41 mL	172.83 mL
0.5 mM	3.46 mL	17.28 mL	34.57 mL
1 mM	1.73 mL	8.64 mL	17.28 mL
5 mM	0.35 mL	1.73 mL	3.46 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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