Trusted by 10,000+ Scientists since 2006


multi-AGC kinase 抑制剂

0 Customer Reviews
产品目录号: A12464


产品名 目录号 价格 数量
AT13148 5mg A12464-5
¥ 1,000.00
AT13148 10mg A12464-10
¥ 1,600.00
AT13148 25mg A12464-25
¥ 3,500.00
AT13148 10mM * 1mL in DMSO A12464-10mM-D
¥ 1,050.00



AT13148 is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A12464
Mechanism of action Inhibitor
分子量 313.78
化学分子式 C17H16ClN3O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1056901-62-2
Synonyms AT 13148, AT-13148
SMILES code C1=CC(=CC=C1C2=CNN=C2)[C@@](CN)(C3=CC=C(C=C3)Cl)O
化学名称 (S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol


AT13148 is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors.
Target Value
PKAIC50: 3nM
ROCK2IC50: 4nM
ROCK1IC50: 6nM
p70S6KIC50: 8nM
Akt1IC50: 38nM
Akt3IC50: 50nM
SGK3IC50: 63nM
RSK1IC50: 85nM
Akt2IC50: 402nM
Chk2IC50: 860nM
AuroraBIC50: 1860nM


Solubility (25°C)* In vitro DMSO 62 mg/mL (197.59 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.87 mL 159.35 mL 318.69mL
0.5 mM 6.37 mL 31.87 mL 63.74 mL
1 mM 3.19 mL 15.93 mL 31.87 mL
5 mM 0.64 mL 3.19 mL 6.37 mL

*The above data is based on the productmolecular weight 313.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.



Keywords:购买 AT13148 | AT13148 供应商 | 订购 AT13148 | AT13148 价格 | AT13148 生产商 | 订单 AT13148 | AT13148 代理商 | 购买 1056901-62-2| 1056901-62-2 供应商 | 订购 1056901-62-2 | 1056901-62-2 价格 | 1056901-62-2 生产商 | 订单 1056901-62-2 | 1056901-62-2 代理商|buy AT13148 | AT13148 Supplier | purchase AT13148 | AT13148 cost | AT13148 manufacturer | order AT13148 | AT13148 distributor | buy 1056901-62-2| 1056901-62-2 Supplier | purchase 1056901-62-2 | 1056901-62-2 cost | 1056901-62-2 manufacturer | order 1056901-62-2 | 1056901-62-2 distributor