Onalespib (AT13387)

目录号: A11062

HSP90 Inhibitor

Onalespib (AT13387) Chemical Structure

CAS NO. 912999-49-6

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,500.00
50 mg
¥ 3,500.00
100 mg
¥ 5,700.00
10mM * 1mL in DMSO
¥ 950.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.
靶点信息
HSP90 (Cell-free assay)
18 nM
In vitro (25°C) DMSO 25 mg/mL (61.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.1 mL 244.2 mL
0.5 mM 4.88 mL 24.42 mL 48.84 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11062
MECHANISM OF ACTION Inhibitor
M. Wt 409.5
Formula C24H31N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 912999-49-6
Synonyms AT-13387
SMILES CC(C)C1=C(C=C(C(=C1)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C)O)O

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