Trusted by 10,000+ Scientists since 2006

AT7519 HCl


CDK 抑制剂

0 Customer Reviews
产品目录号: A11313


产品名 目录号 价格 数量
AT7519 HCl 5mg A11313-5
¥ 800.00
AT7519 HCl 10mg A11313-10
¥ 1,200.00
AT7519 HCl 25mg A11313-25
¥ 2,400.00
AT7519 HCl 50mg A11313-50
¥ 4,400.00
AT7519 HCl 10mM * 1mL in DMSO A11313-10mM-D
¥ 950.00



AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.

AT7519 HCl




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11313
Mechanism of action Inhibitor
分子量 418.7
化学分子式 C16H17Cl2N5O2.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 902135-91-5
Synonyms AT 7519, AT-7519
化学名称 N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide hydrochloride


AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.
Target Value
CDK9/CyclinTIC50: <10nM
CDK5/p35IC50: 13nM
CDK2/CyclinAIC50: 47nM
GSK-3βIC50: 89nM
CDK4/CyclinD1IC50: 100nM
CDK6/CyclinD3IC50: 170nM
CDK1/CyclinBIC50: 210nM
CDK3/CyclinEIC50: 360nM
PI3KβIC50: >1μM
PLK3IC50: >1μM
RETIC50: >1μM
SGKIC50: >1μM
TrkBIC50: >1μM
JAK2IC50: >1μM
CDK7/CyclinH/MAT1IC50: 2.4μM
SAPK2A(p38α)IC50: >10μM
p70S6KIC50: >10μM
PDGFRIC50: >10μM
PDK-1IC50: >10μM
PKBβIC50: >10μM
VEGFR1IC50: >10μM
AuroraAIC50: >10μM
c-AblIC50: >10μM
c-SrcIC50: >10μM
Chk1IC50: >10μM
EGFRIC50: >10μM
FGFR3IC50: >10μM
IRIC50: >10μM
JNK2IC50: >10μM
MAPK1IC50: >10μM
MEK1IC50: >10μM
MetIC50: >10μM


Solubility (25°C) * In vitro DMSO 10 mg/mL (26.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.88 mL 119.42 mL 238.83mL
0.5 mM 4.78 mL 23.88 mL 47.77 mL
1 mM 2.39 mL 11.94 mL 23.88 mL
5 mM 0.48 mL 2.39 mL 4.78 mL

*The above data is based on the productmolecular weight 418.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.



Similar product(s)

Keywords:购买 AT7519 HCl | AT7519 HCl 供应商 | 订购 AT7519 HCl | AT7519 HCl 价格 | AT7519 HCl 生产商 | 订单 AT7519 HCl | AT7519 HCl 代理商 | 购买 902135-91-5| 902135-91-5 供应商 | 订购 902135-91-5 | 902135-91-5 价格 | 902135-91-5 生产商 | 订单 902135-91-5 | 902135-91-5 代理商|buy AT7519 HCl | AT7519 HCl Supplier | purchase AT7519 HCl | AT7519 HCl cost | AT7519 HCl manufacturer | order AT7519 HCl | AT7519 HCl distributor | buy 902135-91-5| 902135-91-5 Supplier | purchase 902135-91-5 | 902135-91-5 cost | 902135-91-5 manufacturer | order 902135-91-5 | 902135-91-5 distributor