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AT7519 trifluoroacetate

CDK 抑制剂

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产品目录号: A15005

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AT7519 trifluoroacetate 10mg A15005-10
¥ 1,200.00
AT7519 trifluoroacetate 25mg A15005-25
¥ 2,400.00
AT7519 trifluoroacetate 100mg A15005-100
¥ 7,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM, less potent to CDK3 and little active to CDK7.

AT7519 trifluoroacetate

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Chemical Information

目录号 A15005
Mechanism of action Inhibitor
分子量 496.27
化学分子式 C18H18Cl2F3N5O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1431697-85-6
Synonyms AT 7519 trifluoroacetate, AT-7519 trifluoroacetate
SMILES code C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.C(=O)(C(F)(F)F)O
化学名称 4-[(2,6-dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide,2,2,2-trifluoroacetic acid

生物活性

Description
AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM, less potent to CDK3 and little active to CDK7.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.15 mL 100.75 mL 201.5mL
0.5 mM 4.03 mL 20.15 mL 40.3 mL
1 mM 2.02 mL 10.08 mL 20.15 mL
5 mM 0.4 mL 2.02 mL 4.03 mL

*The above data is based on the productmolecular weight 496.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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