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AT7519 trifluoroacetate是CDK1、2、4、6和9的多CDK抑制剂，IC50为10-210 nM，对CDK3的效力较低，对CDK7的活性较低。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.15 mL | 100.75 mL | 201.5 mL |
| 0.5 mM | 4.03 mL | 20.15 mL | 40.3 mL |
| 1 mM | 2.02 mL | 10.08 mL | 20.15 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.03 mL |
*The above data is based on the productmolecular weight 496.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15005 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 496.27 |
| Formula | C18H18Cl2F3N5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1431697-85-6 |
| Synonyms | AT 7519 trifluoroacetate, AT-7519 trifluoroacetate |
| SMILES | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.C(=O)(C(F)(F)F)O |
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