|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||24.34 mL||121.72 mL||243.45 mL|
|0.5 mM||4.87 mL||24.34 mL||48.69 mL|
|1 mM||2.43 mL||12.17 mL||24.34 mL|
|5 mM||0.49 mL||2.43 mL||4.87 mL|
*The above data is based on the productmolecular weight 410.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
|Synonyms||AT-7867 dihydrochloride, AT 7867 dihydrochloride|
AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 =…
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50 = 42 nM), with potent and balanced activity.
Perifosine (also KRX-0401) acts as an Akt inhibitor and a PI3K inhibitor.
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, s…
A-674563 is a B/Akt inhibitor with an IC50 of 14 nM and also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respe…
SC 66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt. It exhibits anticancer activity in vit…