AT7867
目录号: A10094
AKT 抑制剂
AT7867 是一种新型且有效的抑制剂，它同时抑制 AKT 和下游激酶 p70 S6 kinase (p70S6K) 以及 protein kinase A。
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生物活性
| Discription | AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A. | ||
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产品信息
| 目录号 | A10094 |
|---|---|
| 分子式 | C20H20ClN3 |
| 分子量 | 337.9 |
| CAS号 | 857531-00-1 |
| SMILES | C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 63 mg/mL (186.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.79 mM) | ||
| In vivo | 15% Captisol, pH 9 | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.59 mL | 147.97 mL | 295.95 mL |
| 0.5 mM | 5.92 mL | 29.59 mL | 59.19 mL |
| 1 mM | 2.96 mL | 14.8 mL | 29.59 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.92 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 857531-00-1 | 857531-00-1 供应商 | 857531-00-1 花费 | 857531-00-1 生产商 | 订购 857531-00-1 | 857531-00-1 代理商