AT7867

目录号: A10094

AKT 抑制剂

AT7867

AT7867 Chemical Structure

CAS NO. 857531-00-1

AT7867是AKT和下游激酶p70 S6激酶(p70S6K)以及蛋白激酶A的新型有效抑制剂。

库存: 现货

规格 价格 数量
10 mg
¥ 1,500.00
25 mg
¥ 3,500.00
50 mg
¥ 6,000.00
100 mg
¥ 9,500.00
10mM * 1mL in DMSO
¥ 1,470.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AT7867是AKT和下游激酶p70 S6激酶(p70S6K)以及蛋白激酶A的新型有效抑制剂。
Targets
Target Value
Akt2IC50: 17nM
PKAIC50: 20nM
Akt1IC50: 32nM
Akt3IC50: 47nM
p70S6KIC50: 85nM
RSK1IC50: >100nM
CDK2IC50: >1μM
GSK-3βIC50: >1μM
c-SrcIC50: >1μM
Chk1IC50: >1μM
EGFRIC50: >1μM
FGFR3IC50: >1μM
MEK1IC50: >1μM
PDK-1IC50: >1μM
PI3KβIC50: >1μM
PLK3IC50: >1μM
RETIC50: >1μM
SGKIC50: >1μM
Tie-2IC50: >1μM
In vitro (25°C) DMSO 68 mg/mL (201.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (14.79 mM)
In vivo 15% Captisol, pH 9 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.59 mL 147.97 mL 295.95 mL
0.5 mM 5.92 mL 29.59 mL 59.19 mL
1 mM 2.96 mL 14.8 mL 29.59 mL
5 mM 0.59 mL 2.96 mL 5.92 mL

*The above data is based on the productmolecular weight 337.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10094
作用机制 Inhibitor (抑制剂)
M. Wt 337.9
Formula C20H20ClN3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 857531-00-1
Synonyms AT-7867
SMILES C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 AT7867 | AT7867 供应商 | 订购 AT7867 | AT7867 价格 | AT7867 生产商 | 订单 AT7867 | AT7867 代理商 | 购买 857531-00-1| 857531-00-1 供应商 | 订购 857531-00-1 | 857531-00-1 价格 | 857531-00-1 生产商 | 订单 857531-00-1 | 857531-00-1 代理商|buy AT7867 | AT7867 Supplier | purchase AT7867 | AT7867 cost | AT7867 manufacturer | order AT7867 | AT7867 distributor | buy 857531-00-1| 857531-00-1 Supplier | purchase 857531-00-1 | 857531-00-1 cost | 857531-00-1 manufacturer | order 857531-00-1 | 857531-00-1 distributor
Rewards