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Atabecestat

Atabecestat

Name: Atabecestat
SKU: A22605

目录号: A22605

BACE1 inhibitor

Atabecestat Chemical Structure

CAS NO. 1200493-78-2

Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction.

库存：现货

规格	价格	数量
5 mg	￥ 4,050.00
10 mg	￥ 6,980.00
50 mg	￥ 20,700.00
100 mg	￥ 40,500.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.22 mL	136.09 mL	272.18 mL
0.5 mM	5.44 mL	27.22 mL	54.44 mL
1 mM	2.72 mL	13.61 mL	27.22 mL
5 mM	0.54 mL	2.72 mL	5.44 mL

*The above data is based on the productmolecular weight 367.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A22605
M. Wt	367.4
Formula	C18H14FN5OS
Solubility	DMSO
Purity	>98%
Storage	at -20°C 2 years
CAS No.	1200493-78-2
Synonyms	JNJ-54861911, JNJ54861911, JNJ 54861911
SMILES	O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)SC=C3)=C2