Atazanavir sulfate (BMS-232632-05)
目录号: A10096
HIV Protease 抑制剂
Atazanavir 是一种 蛋白酶抑制剂(PI)类的抗逆转录病毒药物。与其他抗逆转录病毒药物一样,它用于治疗人类免疫缺陷病毒(HIV)感染。
| Discription | Atazanavir is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). | ||
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| 目录号 | A10096 |
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| 分子式 | C38H52N6O7.H2SO4 |
| 分子量 | 802.9 |
| CAS号 | 229975-97-7 |
| SMILES | CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC.OS(=O)(=O)O |
| 其他名称 | CGP-73547, Reyataz, Zrivada |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 92 mg/mL (114.58 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.45 mL | 62.27 mL | 124.55 mL |
| 0.5 mM | 2.49 mL | 12.45 mL | 24.91 mL |
| 1 mM | 1.25 mL | 6.23 mL | 12.45 mL |
| 5 mM | 0.25 mL | 1.25 mL | 2.49 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2