Atglistatin
目录号: A13814
ATGL 抑制剂
Atglistatin 是一种高效、选择性和竞争性的 脂肪酸甘油三酯脂肪酶 (ATGL) 抑制剂，其 IC50 约为 0.7 μM，用于体外抑制脂解，但在高达 50 μM 的浓度下无毒性。
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生物活性
| Discription | Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with an IC50 of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM. |
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产品信息
| 目录号 | A13814 |
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| 分子式 | C17H21N3O |
| 分子量 | 283.16 |
| CAS号 | 1469924-27-3 |
| SMILES | CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)N(C)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 55 mg/mL (194.09 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (14.11 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.32 mL | 176.58 mL | 353.16 mL |
| 0.5 mM | 7.06 mL | 35.32 mL | 70.63 mL |
| 1 mM | 3.53 mL | 17.66 mL | 35.32 mL |
| 5 mM | 0.71 mL | 3.53 mL | 7.06 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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