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Atipamezole hydrochloride是一种选择性α2肾上腺素受体拮抗剂（α2A、α2B、α2C、α1A和α1B受体的Ki值分别为1.1、1.0、0.89、1300和6500nm）。已经被证明是大脑的渗透剂。
靶点信息
| α2 adrenergic receptor | ||||
| In vitro | DMSO | 12 mg/mL (48.24 mM) | |
| Water | 21 mg/mL (84.42 mM) | ||
| Ethanol | 48 mg/mL (192.96 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.19 mL | 200.96 mL | 401.93 mL |
| 0.5 mM | 8.04 mL | 40.19 mL | 80.39 mL |
| 1 mM | 4.02 mL | 20.1 mL | 40.19 mL |
| 5 mM | 0.8 mL | 4.02 mL | 8.04 mL |
*The above data is based on the productmolecular weight 248.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13902 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 248.8 |
| Formula | C14H16N2.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 104075-48-1 |
| Synonyms | Antisedan |
| SMILES | CCC1(CC2=CC=CC=C2C1)C3=CN=CN3.Cl |
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