Atorvastatin calcium
目录号: A11800
HMG-CoA reductase 抑制剂
阿托伐他汀(立普妥)是一种HMG-CoA还原酶抑制剂,用作降低胆固醇的药物,可以阻断胆固醇的生产。
| Discription | Atorvastatin (Lipitor) is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. | ||
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| 目录号 | A11800 |
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| 分子式 | 2(C33H34FN2O5).Ca |
| 分子量 | 1155.34 |
| CAS号 | 134523-03-8 |
| SMILES | CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2] |
| 其他名称 | Lipitor |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 92 mg/mL (79.63 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+35% PEG300+2% Tween 80+ddH2O | 3 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 8.66 mL | 43.28 mL | 86.55 mL |
| 0.5 mM | 1.73 mL | 8.66 mL | 17.31 mL |
| 1 mM | 0.87 mL | 4.33 mL | 8.66 mL |
| 5 mM | 0.17 mL | 0.87 mL | 1.73 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2