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HMG-CoA reductase 抑制剂

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产品目录号: A13743


产品名 目录号 价格 数量
Atorvastatin 100mg A13743-100
¥ 1,200.00
Atorvastatin 10mM * 1mL in DMSO A13743-10mM-D
¥ 660.00



Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective in treating hypercholesterolemia and certain dyslipidemias.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Atorvastatin 发表的文献 (1)
  • Huang Y, .et al. Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells, Mol Med Rep, 2016, Feb;13(2):1888-94 PMID: 26707502

Chemical Information

目录号 A13743
Mechanism of action Inhibitor
分子量 558.6
化学分子式 C33H35FN2O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 134523-00-5
Synonyms Cardyl
SMILES code CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4
化学名称 N/A


Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective in treating hypercholesterolemia and certain dyslipidemias.


Solubility (25°C)* In vitro DMSO 100 mg/mL (86.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.9 mL 89.51 mL 179.02mL
0.5 mM 3.58 mL 17.9 mL 35.8 mL
1 mM 1.79 mL 8.95 mL 17.9 mL
5 mM 0.36 mL 1.79 mL 3.58 mL

*The above data is based on the productmolecular weight 558.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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