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Atrasentan HCl

Endothelin 拮抗剂 receptor

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产品目录号: A15007

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Atrasentan hydrochloride 10mg A15007-10
¥ 2,400.00
Atrasentan hydrochloride 50mg A15007-50
¥ 8,000.00
Atrasentan hydrochloride 200mg A15007-200
¥ 18,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Atrasentan hydrochloride is an endothelin antagonist receptor (IC50=0.0551 nM, ETA) being developed for the treatment of prostate cancer.

Atrasentan HCl

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Chemical Information

目录号 A15007
Mechanism of action Antagonist
分子量 547.08
化学分子式 C29H39ClN2O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 195733-43-8
Synonyms ABT-627, ABT627, ABT 627
SMILES code CCCCN(CCCC)C(=O)CN1CC(C(C1C2=CC=C(C=C2)OC)C(=O)O)C3=CC4=C(C=C3)OCO4.Cl
化学名称 (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid,hydrochloride

生物活性

Description
Atrasentan hydrochloride is an endothelin antagonist receptor (IC50=0.0551 nM, ETA) being developed for the treatment of prostate cancer.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.28 mL 91.39 mL 182.79mL
0.5 mM 3.66 mL 18.28 mL 36.56 mL
1 mM 1.83 mL 9.14 mL 18.28 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 547.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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