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Atrasentan

ETA 拮抗剂

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产品目录号: A13779

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Atrasentan 5mg A13779-5
¥ 1,500.00
Atrasentan 10mg A13779-10
¥ 2,500.00
Atrasentan 25mg A13779-25
¥ 5,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Atrasentan is an experimental drug that is being studied for the treatment of various types of cancer, including non-small cell lung cancer. It is an endothelin receptor antagonist selective for subtype A (ETA).

Atrasentan

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Chemical Information

目录号 A13779
Mechanism of action Antagonist
分子量 510.62
化学分子式 C29H38N2O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 173937-91-2
Synonyms (+)-A 127722, ABT-627, A 127722, ABT 627
SMILES code CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1C2=CC=C(C=C2)OC)C(=O)O)C3=CC4=C(C=C3)OCO4
化学名称 (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid.

生物活性

Description
Atrasentan is an experimental drug that is being studied for the treatment of various types of cancer, including non-small cell lung cancer. It is an endothelin receptor antagonist selective for subtype A (ETA).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.58 mL 97.92 mL 195.84mL
0.5 mM 3.92 mL 19.58 mL 39.17 mL
1 mM 1.96 mL 9.79 mL 19.58 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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