Atrosab is a humanized IgG1 monoclonal antibody that functions as an antagonist to tumor necrosis factor receptor 1 (TNFR1). It effectively inhibits TNF-alpha-mediated apoptosis and the production of interleukins IL-6 and IL-8, key mediators in inflammatory processes. This antibody has been shown to reduce neurological deficits, highlighting its potential utility in the study of neuroinflammation and other inflammatory diseases. For control experiments, the recommended isotype control is Human IgG1 kappa.
Atrosab is a humanized IgG1 monoclonal antibody that functions as an antagonist to tumor necrosis factor receptor 1 (TNFR1). It effectively inhibits TNF-alpha-mediated apoptosis and the production of interleukins IL-6 and IL-8, key mediators in inflammatory processes. This antibody has been shown to reduce neurological deficits, highlighting its potential utility in the study of neuroinflammation and other inflammatory diseases. For control experiments, the recommended isotype control is Human IgG1 kappa.
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