Atrosimab (ATM-001) is an engineered Fv-Fc1?? fusion protein that exhibits high-affinity binding to human TNF receptor 1 (TNFR1), demonstrated by an EC50 of 0.37 nM. This biologic effectively inhibits TNF-induced activation of TNFR1, highlighting its utility in the investigation of chronic inflammatory diseases. Atrosimab represents a valuable tool for researchers studying the molecular pathways involved in inflammation and immune response.
Atrosimab (ATM-001) is an engineered Fv-Fc1?? fusion protein that exhibits high-affinity binding to human TNF receptor 1 (TNFR1), demonstrated by an EC50 of 0.37 nM. This biologic effectively inhibits TNF-induced activation of TNFR1, highlighting its utility in the investigation of chronic inflammatory diseases. Atrosimab represents a valuable tool for researchers studying the molecular pathways involved in inflammation and immune response.
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