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Atuveciclib (BAY-1143572)

Atuveciclib (BAY-1143572)

Name: Atuveciclib (BAY-1143572)
SKU: A16810

目录号: A16810

Selective PTEFb/CDK9 抑制剂

Product Citations (1)

Atuveciclib (BAY-1143572) Chemical Structure

CAS NO. 1414943-88-6

Atuveciclib (BAY-1143572)是目前处于I期的PTEFb/CDK9的高度选择性，有效且可口服的抑制剂。

库存：现货

规格	价格	数量
2 mg	￥ 1,200.00
5 mg	￥ 2,200.00
10 mg	￥ 3,800.00
50 mg	￥ 12,000.00

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生物活性

Atuveciclib (BAY-1143572)是目前处于I期的PTEFb/CDK9的高度选择性，有效且可口服的抑制剂。

溶解度 *

In vitro	DMSO	69 mg/mL (178.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.81 mL	129.06 mL	258.11 mL
0.5 mM	5.16 mL	25.81 mL	51.62 mL
1 mM	2.58 mL	12.91 mL	25.81 mL
5 mM	0.52 mL	2.58 mL	5.16 mL

*The above data is based on the productmolecular weight 387.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16810
作用机制	Inhibitor (抑制剂)
M. Wt	387.43
Formula	C18H18FN5O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1414943-88-6
Synonyms	BAY 1143572, BAY-1143572
SMILES	O=S(C)(CC1=CC=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=C1)=N