Atuveciclib (BAY-1143572)

Name: Atuveciclib (BAY-1143572)
SKU: A16810
Price: 420 CNY
Rating: 5 (1 reviews)

目录号: A16810

Selective PTEFb/CDK9 抑制剂

1 篇发表文献

Atuveciclib（也称为BAY1143572）是一种高度选择性、高效且可口服的PTEFb/CDK9抑制剂，目前处于I期临床试验阶段。

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Grouped product items
规格	价格	库存
1mg	¥420.00	现货
2mg	¥805.00	现货
5mg	¥1,435.00	现货
10mg	¥2,380.00	现货
25mg	¥4,480.00	现货
50mg	¥5,950.00	现货
100mg	¥8,225.00	现货
*10mM 1mL in DMSO**	¥1,610.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Atuveciclib (BAY-1143572)发表的1篇文献

Cole Schonhofer, .et al. , Biochem Pharmacol, 2021, Apr;186:114462 PMID: 33577894

生物活性

Discription

Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16810
分子式	C18H18FN5O2S
分子量	387.43
CAS号	1414943-88-6
SMILES	O=S(C)(CC1=CC=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=C1)=N
其他名称	BAY 1143572, BAY-1143572
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	69 mg/mL (178.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.81 mL	129.06 mL	258.11 mL
0.5 mM	5.16 mL	25.81 mL	51.62 mL
1 mM	2.58 mL	12.91 mL	25.81 mL
5 mM	0.52 mL	2.58 mL	5.16 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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