Auglurant
目录号: A20958
mGlu5 拮抗剂
Auglurant (VU0424238) 是一种新型且选择性的 mGlu5 拮抗剂,其在大鼠体内的 IC50 值为 11 nM,而在人体内的 IC50 值为 14 nM。Auglurant (VU0424238) 具有可接受的 CNS 渗透性。
| Discription | Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration. | |||||
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| Cell Research |
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| 目录号 | A20958 |
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| 分子式 | C16H12FN5O2 |
| 分子量 | 325.3 |
| CAS号 | 1396337-04-4 |
| SMILES | CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1 |
| 其他名称 | VU0424238, VU 0424238, VU-0424238 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2