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Auglurant

目录号: A20958
mGlu5 拮抗剂
Auglurant (VU0424238) 是一种新型且选择性的 mGlu5 拮抗剂,其在大鼠体内的 IC50 值为 11 nM,而在人体内的 IC50 值为 14 nM。Auglurant (VU0424238) 具有可接受的 CNS 渗透性。
Grouped product items
规格 价格 库存 数量
1mg
¥2,205.00
现货
5mg
¥3,080.00
现货
10mg
¥5,460.00
现货
25mg
¥9,975.00
现货
50mg
¥12,985.00
现货
100mg
¥17,465.00
现货
10mM * 1mL in DMSO
¥2,975.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20958
分子式 C16H12FN5O2
分子量 325.3
CAS号 1396337-04-4
SMILES CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1
其他名称 VU0424238, VU 0424238, VU-0424238
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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